期刊论文

Experimental study of Shire particles on relieving inflammatory and itching

中文

湖南中医药大学学报

1674-070X

2011

31

1

40-42

10.3969/j.issn.1674-070X.2011.01.011.040.03

湖南中医药大学“中药学”重点学科资助；

本校为第一机构

目的 研究湿热颗粒抗炎止痒的作用.方法 通过湿热颗粒对二甲苯所致小鼠耳廓肿胀模型、角叉菜胶所致大鼠足跖肿胀模型的影响,观察湿热颗粒对炎症的影响;通过湿热颗粒对葡聚糖-40所致的小鼠瘙痒模型、磷酸组胺豚鼠致瘁模型的影响,观察湿热颗粒对瘙痒的影响.结果 与模型组比较,湿热颗粒各剂量组能显著降低二甲苯所致的小鼠耳廓肿胀度,差异具有统计学意叉(P＜0.05);湿热颗粒中剂量组能显著降低角叉莱胶致炎后30 min,1、2、3、4、6 h大鼠足趾肿胀率,差异具有统计学意义(P＜0.05);湿热颗粒中剂量、高剂量组能显著延长葡聚糖-40所致小鼠瘙痒的潜伏期及减少其瘙瘁次数,差异具有统计学意义(P＜0.01);湿热...

Objective To study the effects of Shire particles on relieving inflammatory and itching.Methods According to the actions of the particles on ear swelling model of mice induced by xylene and paw edema model of rats induced by carrageenan,the effects of the particles on inflammatory was measured;according to the model of the actions of the particles on itching in mice induced by dextran-40 and in guinea pig induced by Histamine phosphate,the effects of the particles on itching was measured.Results Compared with model group,each dose groups of Shi...