期刊论文

Study on anti-biosis activity of modified Cnidium monnieri decoction

中文

湖南中医药大学学报

1674-070X

2011

31

11

24-26

10.3969/j.issn.1674-070X.2011.11.007.024.03

2009SK3120:科技计划 2010014:湖南省卫生厅科学研究项目 :湖南中医药大学校级青年教师科研基金

本校为第一机构

目的 研究治疗老年性阴道炎中药经方蛇床子汤加味配伍的抗菌作用.方法 运用琼脂扩散法、液体稀释法、琼脂稀释法定性和定量检测蛇床子汤加味配伍1号方、2号方、3号方及单味药白矾对金黄色葡萄球菌、大肠埃希菌及白假丝酵母菌的抗菌作用.结果 在琼脂扩散法中1号方对金黄色葡萄球菌、大肠埃希菌及白假丝酵母菌抗菌作用优于2号方及3号方；单味药白矾对3种菌抑菌作用优于1号方,差异有统计学意义(P＜0.05).液体稀释法中,1号方对金黄色葡萄球菌、大肠埃希菌的MIC值为31.25 mg/mL,对上述两种菌株MBC值为31.25 mg/mL.结论 蛇床子汤加味配伍1号方为优势复方,有较明显的抗菌作用.

Objective To study the anti-biosis effects of modified traditional formula Cnidium monnieri decoction for senile vaginitis.Methods With the Agar diffusion method,liquid dilution method,agar dilution method qualitative and quantitative detection,the antibacterial effects of 1st,2nd and 3rd Cnidium monnieri decoctions and single drug alumen were detected for Staphylococcus aureus,Escherichia coli and Candida albicans.Results The anti-biosis effect of 1th decoction for Staphylococcus aureus,Escherichia coli and Candida albicans were better than 2n...