期刊论文

Effect of aerobic exercise and Pingfeifang on lipid metabolism and insulin resistant of DIO rats

中文

湖南中医药大学学报

1674-070X

2011

31

8

3-5

10.3969/j.issn.1674-070X.2011.08.001

中医诊断学重点学科、中医病证重点实验室建设项目资助；

本校为第一机构

目的 评价有氧运动与平肥方对高脂饮食所致肥胖大鼠(DIO)脂肪代谢和胰岛素抵抗的影响.方法 SD雄鼠10只予普饲喂养作为空白对照组,30只经高脂饮食诱导成功的DIO雄鼠随机分为肥胖对照组、二甲双胍组、有氧运动+平肥方干预组,每组10只.实验干预6周后,检测各组大鼠体质量(BW)、空腹血糖(FPG)、总胆固醇(TCH)、甘油三酯(TG)、极低密度脂蛋白(VLDL)、空腹胰岛素(FINS)、HOMA-指数(HOMA-index)等.结果 与对照组比较,DIO大鼠体质量、脂代谢各指标、血糖、胰岛素等差异具有统计学意义(P＜0.01);干预数周后,与肥胖对照组比较,二甲双胍组和综合组均可显著降低DIO大鼠体质量,并可显著改善脂代谢诸指标及血糖...

Objective To evaluate the effect of combined therapeutic of aerobic exercise and Pingfeifang on lipid metabolism and insulin resistant of diet-induced-obesity （DIO） rats. Methods 10 SD male rats used for blank contrast group, while 30 DIO male rats were divided into DIO group, mclbine group and combined therapeutic of aerobic exercise and Pingfeifang group （therapeutic group）, each group has 10 rats. Aider 6 weeks intervening, the rats body weight（BW）, fasting plasma glucose （FPG）, total cholesterol （TCH）, triglyceride（TG）, very low...