期刊论文

Effects of Electro-acupuncture on expression of apoptosis-related factors Bcl-2 and Bax in bladder tissues of rats with neuropathic bladder after sacral spinal cord injury

中文

湖南中医药大学学报

1674-070X

2013

33

11

82-85

10.3969/j.issn.1674-070X.2013.11.023.082.04

13JJ3098:湖南省自然科学基金 1200264:湖南省教育厅科学研究项目 201109:湖南省中医药科研项目

本校为第一机构

目的 观察电针次髎、中极、三阴交穴对骶髓损伤后神经源性膀胱（逼尿肌无反射型）大鼠膀胱组织中B 淋巴细胞蛋白-2（bcl-2）及Bcl 相关X 蛋白（bax）表达的影响,以探讨电针治疗该病的可能机制.方法 将SD 雌性大鼠40只,随机抽取10 只为空白组,其余造模成功后随机分为模型组、电针穴位组和电针对照点组,每组10 只.术后第15 天起电针穴位组、电针对照点组分别施以每日1 次治疗,治疗7 次后取膀胱组织行Elisa 法检测bcl-2 及bax 在膀胱组织中的表达.结果 电针治疗后各组膀胱逼尿肌组织中,模型组、电针穴位组和电针对照点组bcl-2 及bax 表达均较空白组高（P〈0.01）,电针穴位组和电针对照点组bcl-2 表...

Objective To explore the mechanisms of electro-acupuncture therapy by observing the effects of electro-acupuncture at Ciliao, Zhongji, Sanyinjiao acupoint on the expression of bcl-2 and bax in bladder tissues of rats with neurogenic bladder （detrusor areflexia type） after sacral spinal cord injury. Methods 10 SD rats were randomly selected as blank group from 40 SD female rats. The others were randomly divided into model group, electro-acupuncture group and control point group after modeled, with 10 rats in each group. The rats in electro-acu...