期刊论文

The TCM Syndrome Distribution Characteristic of 1868 Chronic Hepatitis B Patients and the Correlation Analysis with Virology Indices of Serum by Logistic Regression

中文

湖南中医药大学学报

1674-070X

2014

34

4

24-28

10.3969/j.issn.1674-070X.2014.04.008.024.05

湖南省科技厅课题（2011FJ3216）；

本校为第一机构

目的 运用临床流行病学方法分析慢性乙型肝炎(Chronic hepatitis B,CHB)患者中医证候分布特征,并探讨其主要中医证型与血清病毒学指标的相关性.方法 基于多中心、大样本的横断面调查方法回顾性分析1 868例CHB患者的中医证候分布特征,并运用二元logistic逐步回归分析以探讨其常见证型与病毒学指标的相关性.结果 CHB的常见中医证型为肝郁脾虚证(42.3％)、湿热蕴结证(23.1％)、肝郁气滞证(11.9％)、肝肾阴虚证(5.7％)、瘀血阻络证(5.3％)、脾肾阳虚证(3.4％);HBeAg与湿热蕴结证呈正相关(OR=9.010,P＜0.01),与肝郁气滞证(OR=0.335,P＜0.01)、肝肾阴虚证(OR=0.215,P＜0.01)、瘀血阻络证(OR=0.506,P＜...

Objective To analyze TCM syndrome distribution characteristic of ChronicHepatitis B （CHB） by clinical epidemiology method, and explore the correlation between main TCM syndro me types of CHB and virology indices of serum. Methods The distribution characteristic of TCM syndromes of 1868 cases were retrospectively analyzed based on polycentric and large cross-sectional survey method, and using binary stepwise logistic regression by SPSS 19.0 Software to analyze the correlation. Results There were six familiar syndrome types of CHB： Liver depre...