"Dysphoria" is one of the common symptoms in "treatise on febrile diseases". The "dysphoria" in "treatise on febrile diseases" was classified by six meridians: Taiyang, Yangming, Taiyin, Shaoyin and Jueyin. The "dysphoria" which could not be concluded by six meridians, was classified by six-channel differentiation. The symptoms of the "dysphoria" of six-channel diseases also have characteristics of fundamental symptom, while six-channel diseases should be identified as cold and heat, deficiency and excess, then their treatment base...