目的合成乙酰阿魏酸丹皮酚酯。方法阿魏酸经乙酰化后与SOCl2反应制备成酰氯,再以三乙胺为催化剂,在丙酮溶剂中乙酰阿魏酸酰氯与丹皮酚拼合成酯。结果经IR和1H-NMR确定了目标化合物结构,当乙酰阿魏酸和丹皮酚的摩尔比为1∶1,反应时间为3 h,温度为5℃,三乙胺用量为15 m L,目标化合物的收率为62.8%。结论以三乙胺为催化剂合成乙酰阿魏酸丹皮酚酯,反应条件温和,工艺简单,收率较好,利于工业化生产。
摘要(英文)：
Objective To synthesize the acetylferulic paeonol ester. Methods The ferulic acid was first acetylated then halogenated with SOCl2 to prepare the acetylferuloyl chloride. The acetylferuloyl chloride and paeonol were mixed in acetone and catalyzed by triethylamine to be finally esterificated to the acetylferulic paeonol ester. Results The structure of targeted compound was identified by IR and1H-NMR, and the result showed that the yield of target compound was 62.8%when the mole ratio of the starting materials of acetylferulic acid and paeonol wa...
