Objective Using the cardiopulmonary coupling (CPC) to analysis the sleep monitoring system and observe the clinical efficacy of five-elements music merge antidepressants to treat the depression associated with sleep disorders. Methods Seventy depressive patients associated with sleep disorders were randomly divided into two groups. The observation group was treated with five-elements music merge antidepressants. The control group was treated with antidepressants only. After 4 weeks course treatment, the CPC monitoring value, HAMD and PSQI sco...