Objective To explore the current status of breast cancer targeted drug therapy in Fujian province, and analyze the economic burden of the treatment, so to provide a reference for the establishment of medical insurance policy of major catastrophic disease. Methods Obtaining the breast cancer patients' data of informational system at nine cities' medical insurance management center in Fujian province from 2011 to 2015, and the expense of treatment. A statistical analysis was performed by using SPSS21.0. Results Herceptin usage by 389 rising in 2011 to 2015 in 2398, showed a trend of sustained gr...