期刊论文

Clinical Observation of Xiongcan Yishen Prescription Combined with Low-dose Testosterone Supplementation in Treatment of Late-Onset Hypogonadism in Males

中文

湖南中医药大学学报

1674-070X

2018

38

8

903-907

10.3969/j.issn.1674-070X.2018.08.015

国家自然科学基金（81673984）； 湖南省教育厅优秀青年项目（16B200）； 湖南中医药大学研究生创新课题（1023-0002001032）;湖南中医药大学“一方研究生科研创新项目”（YF201701）；

本校为第一机构

目的 观察雄蚕益肾方联合小剂量睾酮补充治疗男性迟发性性腺功能减退症（late-onset hypogonadism,LOH）的临床疗效。方法 将符合LOH诊断标准的106例患者按随机数字表法分为对照组和试验组各53例,对照组采用常规睾酮补充治疗,试验组服用雄蚕益肾方联合小剂量睾酮补充治疗,疗程均为3个月。比较两组治疗前后的老年男性症状量表（AMS）评分、血清性激素水平及中医证候评分。结果 （1）两组治疗后较治疗前AMS各项症状评分和总分均有显著下降（P〈0.05）,总睾酮（TT）水平及睾酮分泌指数（TSI）值均显著提高（P〈0.05）,促黄体生成素（LH）、卵泡刺激素（FSH）水平均下降（P〈0.05）,且试验组改善效果...

Objective To evaluate the clinical efficacy of Xiongcan Yishen Prescription combined with low-dose testosterone supplementation in the treatment of late-onset hypogonadism （LOH） in males. Methods A total of 106 male patients diagnosed with LOH were randomly and equally divided into control group and experimental group using a random number table. The control group was treated with routine testosterone supplementation therapy for 3 months, while the experimental group was treated with Xiongcan Yishen Prescription combined with low-dose testost...