期刊论文

Effect of Aerobic Exercise Combined with Shenfu Injection on NT-proBNP in Rats with Cardiomyopathy-lnduced Heart Failure

中文

湖南中医药大学学报

1674-070X

2018

38

6

641-644

10.3969/j.issn.1674-070X.2018.06.007

81373550:国家自然科学基金 81774208:国家自然科学基金 81503627:国家自然科学基金 2016-298:湖南省大学生研究性学习和创新性实验计划 2015-32:青年教师科研项目

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目的 观察有氧运动联合参附注射液对心肌病心衰大鼠N末端脑钠素前体(NT-proBNP)的影响.方法 50只SD大鼠随机选取10只作为对照组,其余40只腹腔注射盐酸多柔比星建立心肌病心衰模型.造模成功后,将造模存活大鼠随机分为模型组、参附注射液组、有氧运动组、有氧运动联合参附注射液组,每组9只.以上各组分别用生理盐水、参附注射液、有氧运动、有氧运动联合参附注射液干预4周,用Elisa法检测NT-proBNP指标.结果 成功复制心肌病心衰大鼠模型,有氧运动联合参附注射液组大鼠死亡率最低.模型组NT-proBNP水平较高,与其他各组比较差异有统计学意义(P＜0.05);参附注射液组与有氧运动组NT-proBNP比较,差异无统计...

Objective To observe the effect of aerobic exercise combined with Shenfu injection on N-terminal pro brain natriuretic peptide （NT-proBNP） in rats with cardiomyopathy-induced heart failure. Methods The 50 SD rats were randomly selected 10 rats as the control group, and the others were built for the cardiomyopathy model by intraperitoneal injection of doxorubicin hydrochloride. After the model was successful, the model group was randomly divided into the model group, the Shenfu injection group, the aerobic exercise group and the aerobic exerci...