期刊论文

中文

湖南中医药大学学报

1674-070X

2018

38

11

1243-1247

10.3969/j.issn.1674-070X.2018.11.005

国家自然科学基金项目（81173327/H2718）.

本校为第一机构

目的 对比观察电针阳陵泉、上巨虚、下巨虚、足三里穴对急性胆囊炎 (AC) 模型豚鼠血清肿瘤坏死因子-α (TNF-α) 及胆囊组织中烟碱型乙酰胆碱受体α7信使核糖核酸 (nAchRα7 mRNA) 表达的影响, 探讨胆之下合穴阳陵泉治疗对应腑病是否存在相对特异性.方法 72只健康豚鼠随机分为空白、模型、阳陵泉、上巨虚、下巨虚、足三里组六组, 12只/组, 雌雄各半.除空白组外均于胆囊注射大肠杆菌建立豚鼠急性胆囊炎模型, 成模后予电针治疗5 d, 取胆囊组织行HE染色, 镜下观察形态学变化, ELISA法检测血清TNF-α水平, RT-PCR检测胆囊nAchRα7 mRNA的表达.结果 与空白组比较, HE染色镜下观察可见其他组胆囊组织出...

Objective To compare the effects of electroacupuncture at Yanglingquan, Shangjuxu, Xiajuxu, and Zusanli points on serum tumor necrosis factor-α (TNF-α) and m RNA expression of α7 nicotinic acetylcholine receptor (nAChR α7) in the gallbladder in a guinea pig model of acute cholecystitis (AC), and to explore whether Yanglingquan, the lower He-sea point of the gallbladder, is relatively specific for treating the corresponding visceral disease. Methods Seventy-two healthy guinea pigs were randomly and equally divided into blank group, model gro...