期刊论文

Analysis of Petroleum Ether Extract from Prunella Vulgaris L.Fruit by GC-MS and Its Anti-inflammatory Activity

中文

湖南中医药大学学报

1674-070X

2020

40

6

689-692

10.3969/j.issn.1674-070X.2020.06.009

2017YFC1701900:国家重点研发计划 kq1801046:长沙市科技计划 kq1804027:长沙市科技计划

本校为第一机构

目的 表征夏枯草果实石油醚提取物化学成分,评价其抗炎活性.方法 采用气相色谱-质谱联用(GC-MS)对夏枯草果实的化学成分进行分析.建立RAW264.7细胞炎症模型,评价其抗炎效果.结果 共鉴定夏枯草果实石油醚提取物中19个化学成分.抗炎活性发现,夏枯草果实石油醚提取物均具有明显的抗炎效果.结论 夏枯草果实石油醚提取物成分及抗炎活性均具一定差异性.

Objective To characterize the chemical constituents of petroleum ether extract from prunella vulgaris L.fruit,and to evaluate its anti-inflammatory activity.Methods GC-MS was used to detect the chemical constituents of the fruits of prunella vulgaris L.The RAW264.7 cell inflammation model was established,and its anti-inflammatory effect was evaluated.Results A total of 19 chemical compounds were identified from Prunella vulgaris L.The research on anti-inflammatory activity found that the petroleum ether extracts of Prunella vulgaris L.had significant anti-inflammatory effects.Conclusion The co...