期刊论文

Correlation of TGF-β/Smads signaling pathways with intestinal microecological imbalance of chronic heart failure based on "the paring between the heart and small intestine" in Chinese medicine

中文

湖南中医药大学学报

1674-070X

2023

43

03

400-404

10.3969/j.issn.1674-070X.2023.03.006

81874375:国家自然科学基金 2020JJ4464:湖南省自然科学基金项目 2021024:湖南省中医药科研计划重点项目 17A163:湖南省教育厅科研计划重点项目 2020XJJJ002:湖南中医药大学校级科研重点项目

本校为第一机构

慢性心力衰竭作为多种心血管疾病发展到终末期的疾病阶段,已成为当今全球高发病率和病死率的主要原因之一。肠道菌群与慢性心力衰竭的发生发展关系密切,转化生长因子-β(transforming growth factor-β, ...展开更多 慢性心力衰竭作为多种心血管疾病发展到终末期的疾病阶段,已成为当今全球高发病率和病死率的主要原因之一。肠道菌群与慢性心力衰竭的发生发展关系密切,转化生长因子-β(transforming growth factor-β, TGF-β)/Smads信号通路和/或肠道菌微生态失衡能诱导心肌纤维化,促进慢性心力衰竭的发生发展。本文从中医“心合小肠”理论出发,以TGF-β/Smads信号通路调控慢性心力衰竭为主线,探...

As the final stage in the development of various cardiovascular diseases, chronic heart failure has become one of the main causes of high morbidity and mortality worldwide. The transforming growth factor-β(TGF-β)/Smads signaling pathways and/or the intestinal microecolo...MORE As the final stage in the development of various cardiovascular diseases, chronic heart failure has become one of the main causes of high morbidity and mortality worldwide. The transforming growth factor-β(TGF-β)/Smads signaling pathways and/or the intestinal microeco...