期刊论文

Clinical efficacy and metabolomics of Chuanjin Jieyu Decoction in treating mild to moderate depression

中文

湖南中医药大学学报

1674-070X

2023

43

05

940-948

10.3969/j.issn.1674-070X.2023.05.028

202103090662:湖南省卫生计生委科研课题 202203094023:湖南省卫生计生委科研课题 2021SK4022:湖南省临床医学研究中心项目 2020SK2123:湖南省重点研发项目

本校为第一机构

目的分析川金解郁汤(Chuanjin Jieyu Decoction,CJJYD)对轻中度抑郁(mild to moderate depression,MTMD)患者干预前后的代谢物差异性及相关代谢物变化规律,为CJJY...展开更多 目的分析川金解郁汤(Chuanjin Jieyu Decoction,CJJYD)对轻中度抑郁(mild to moderate depression,MTMD)患者干预前后的代谢物差异性及相关代谢物变化规律,为CJJYD治疗MTMD提供科学依据。方法纳入湖南省脑科医院2020年1月至12月期间23名MTMD患者作为病例组(Dep组)、健康人21名作为对照组(CT组),Dep组予以CJJYD干预6周,早晚各服1剂,每次100 mL。采用汉密尔顿抑郁量表(Hamilton depression scale,HAMD)和抑郁自评量表(self-...

Objective To analyze differential metabolites and the associated metabolite change rules of Chuanjin Jieyu Decoction(CJJYD)in treating mild to moderate depression(MTMD)both before and after intervention,and to provide scientific bases for treating MTMD patients with CJJ...MORE Objective To analyze differential metabolites and the associated metabolite change rules of Chuanjin Jieyu Decoction(CJJYD)in treating mild to moderate depression(MTMD)both before and after intervention,and to provide scientific bases for treating MTMD patients with CJJYD.Methods A total of 23 MTMD patients received in H...