This work was supported by the Project of Technology Department of Hunan Province of China (2013SK3216), the college fund of The Second People's Hospital of Hunan Province and National Natural Science Foundation of China 81171597 And 81371834.
机构署名：
本校为其他机构
院系归属：
临床医学院
摘要：
We investigated the effects of Pseudomonas aeruginosa mannose-sensitive hemagglutinin (PA-MSHA) on the proliferation and invasion of human cervical cancer cell lines, as well as the molecular pathways underlying these effects. MTT cell proliferation assays revealed a time- and concentration-dependent cytotoxic effect of PA-MSHA on HeLa cells but not H8 cells. Flow cytometry with propidium iodide and annexin-V-fluorescein isothiocyanate labeling (FITC) indicated that various concentrations of PA-MSHA could induce apoptosis and G2-M cell cycle ar...
