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Antioxidant capacity and phenolic compounds of Lonicerae macranthoides by HPLC–DAD–QTOF-MS/MS

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成果类型:
期刊论文
作者:
Hu, Xin;Chen, Lin;Shi, Shuyun;Cai, Ping;Liang, Xuejuan;...
通讯作者:
Shi, SY;Zhang, SH
作者机构:
[Shi, SY; Shi, Shuyun; Hu, Xin] Cent S Univ, Coll Chem & Chem Engn, Changsha 410083, Hunan, Peoples R China.
[Zhang, Shuihan; Liang, Xuejuan; Chen, Lin; Cai, Ping; Zhang, SH] Hunan Acad Chinese Med, Res Inst Chinese Med, Changsha 410013, Hunan, Peoples R China.
通讯机构:
[Shi, SY ] C
[Zhang, SH ] H
Cent S Univ, Coll Chem & Chem Engn, Changsha 410083, Hunan, Peoples R China.
Hunan Acad Chinese Med, Res Inst Chinese Med, Changsha 410013, Hunan, Peoples R China.
语种:
英文
关键词:
1,1 diphenyl 2 picrylhydrazyl;1,4 di o caffeoylquinic acid;2,2' azinobis(3 ethylbenzothiazoline 6 sulfonic acid);3,4 di o caffeoylquinic acid;3,4,5 tri o caffeoylquinic acid;3,5 di o caffeoylquinic acid;4 hydroxybenzoic acid;4 o caffeoylquinic acid;4,5 di o caffeoylquinic acid;acetic acid ethyl ester;antioxidant;butanol;butylcresol;caffeic acid;chlorogenic acid;chrysoeriol 7 o glucoside;flavonoid;gallic acid;isoquercitrin;Lonicera extract;Lonicerae macranthoides extract;luteolin;luteolin 7 glucoside;neochlorogenic acid;oxygen;petroleum ether;phenol derivative;protocatechuic acid;quercetin;unclassified drug;water;antioxidant;phenol derivative;ABTS radical scavenging assay;antioxidant activity;Article;comparative study;controlled study;diode;diode array detector;DPPH radical scavenging assay;high performance liquid chromatography;IC50;in vitro study;Lonicera;Lonicerae macranthoides;molecular weight;nonhuman;oxidation reduction reaction;priority journal;tandem mass spectrometry;chemistry;high performance liquid chromatography;Lonicera;procedures;tandem mass spectrometry;Antioxidants;Chromatography, High Pressure Liquid;Lonicera;Phenols;Tandem Mass Spectrometry
期刊:
Journal of Pharmaceutical and Biomedical Analysis
ISSN:
0731-7085
年:
2016
卷:
124
期:
1
页码:
254-260
基金类别:
This work was sponsored by the National Natural Science Foundation of China (21275163), Program of Survey and Monitoring of Chinese Medicines for National Drugs ([2011] 76), Administration of Traditional Chinese Medicine of Hunan (201506), and Collaboration and Innovation Center for Digital Chinese Medicine in Hunan.
机构署名:
本校为其他机构
摘要:
Lonicerae macranthoides with strong antioxidant activity is commonly used in traditional Chinese medicine and folk tea/beverage. However, detailed information about its antioxidant activity and bioactive compounds is limited. Then at first, we comparatively evaluated total phenolic content (TPC), total flavonoid content (TFC) and antioxidant activities of water extract, petroleum ether, ethyl acetate and n-butanol fractions of L. macranthoides. Ethyl acetate fraction exhibited the highest level of TPC (207.38 mg GAE/g DW), TFC (53.06 mg RE/g DW...

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