期刊论文

Wang, Xianwen;He, YC

英文

Journal of Ethnopharmacology

0378-8741

2024

319

Pt 3

117343

10.1016/j.jep.2023.117343

This work was supported in part by the National Natural Science Foundation of China (No.82104941,81973914), the Natural Science Foundation of Hunan Province (No.2022JJ30447,2023JJ30449, 2023JJ40500 and 2023JJ30475), the Natural Science Foundation of Changsha City (No.kq2208206), the Project of Hunan Provincial Department of Education (No.21B0359, 22A0254), Chinese Academy of Engineering Academician Liang Liu's Workstation of Hunan University of Chinese Medicine (No.22YS001), Firstclass CRediT authorship contribution statement Fangliang Zhou: Conceptualization, Methodology, Formal analysis, acquisition, Writing – original draft. Wen Wang: Methodology, Formal analysis, Writing – original draft. Runshi Xu: Formal analysis, Methodology. Liu Liu: Formal analysis, Validation, Methodology. Ting Lin: Methodology, Formal analysis. Lan He: Methodology, acquisition. Le Tang: Methodology. Xianwen Wang: Conceptualization, Writing – review & editing, acquisition. Yingchun He: Conceptualization,

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ETHNOPHARMACOLOGICAL RELEVANCE: Yiqi Jiedu formula (YQJDF), rooted in the traditional Chinese medicinal principle of "tonifying qi and detoxifying", is remarkably efficacious in the clinical treatment of nasopharyngeal carcinoma (NPC). Previous studies have shed light on some of its anti-NPC effects and mechanisms, but the responsible pharmacological substances and their precise mechanisms of action remain unclear. AIM OF THE STUDY: The purpose of this study was to identify components of YQJDF that entered the bloodstream and to investigate their mechanisms of action against NPC through networ...