Seco-dammarane triterpenoids from the leaves of Cyclocarya paliurus

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期刊论文

作者：

Chen, Yan-jiao;Na, Liang;Fan, Jialong;Zhao, Jianping;Hussain, Nusrat;...

通讯作者：

Wang, Wei;Liu, Bin

作者机构：

[Hussain, Nusrat; Chen, Yan-jiao; Li, Bin; Wang, Wei; Jian, Yu-qing; Yuan, Hanwen; Na, Liang] Hunan Univ Chinese Med, Sch Pharm, Sinopakistan TCM & Ethnomed Res Ctr, TCM & Ethnomed Innovat & Dev Lab, Changsha 410208, Hunan, Peoples R China.

[Liu, Bin; Fan, Jialong] Hunan Univ, Coll Biol, Hunan Prov Key Lab Plant Funct Genom & Dev Regulat, Changsha 410082, Hunan, Peoples R China.

[Na, Liang] Hunan Food & Drug Vocat Coll, Coll Tradit Chinese Med, Changsha, Hunan, Peoples R China.

[Khan, Ikhlas; Zhao, Jianping] Univ Mississippi, Res Inst Pharmaceut Sci, Natl Ctr Nat Prod Res, University, MS 38677 USA.

[Hussain, Nusrat; Choudhary, M. Iqbal] Univ Karachi, Int Ctr Chem & Biol Sci, HEJ Res Inst Chem, Karachi, Pakistan.

通讯机构：

[Wang, Wei; Liu, Bin] H

Hunan Univ Chinese Med, Sch Pharm, Sinopakistan TCM & Ethnomed Res Ctr, TCM & Ethnomed Innovat & Dev Lab, Changsha 410208, Hunan, Peoples R China.

Hunan Univ, Coll Biol, Hunan Prov Key Lab Plant Funct Genom & Dev Regulat, Changsha 410082, Hunan, Peoples R China.

语种：

英文

关键词：

Cyclocarya paliurus;Juglandaceae;Seco-dammarane triterpenoids;Cytotoxicity

期刊：

Phytochemistry

ISSN：

0031-9422

年：

2018

卷：

145

页码：

85-92

DOI：

10.1016/j.phytochem.2017.10.013

基金类别：

National Natural Science Foundation of People's Republic of ChinaNational Natural Science Foundation of China (NSFC) [81374062, 85673179]; National Ministry of Education Overseas Returnees Star-up Fund [2013-693]; United States Department of Agriculture, Discovery & Development of Natural Products for Pharmaceutical & Agricultural Applications [58-6060-6-015]

机构署名：

本校为第一且通讯机构

院系归属：

药学院

摘要：

The leaves of Cyclocarya paliurus with sweet taste are often used as herbal tea in People's Republic of China. In this study eight previously undescribed seco-dammarane type triterpenoids, cyclocariols A-H along with seven known compounds were isolated and characterized from its leaves. A possible biogenetic pathway for seco-dammarane type triterpenoids formation has been discussed. Cyclocariols A-H were evaluated for their cytotoxicities against human liver (SMMC-7721) and breast cancer (BT-549) cell lines. Cyclocariols A, B, E, and H were also tested against human colon tumor (HCT-116) cell ...

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Seco-dammarane triterpenoids from the leaves of Cyclocarya paliurus

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