期刊论文

The Effect on Endothelin and Nitricoxide of Hyperlipemia Rabbit through Moxibustion with Medicinal Cake

中文

中国中医药信息杂志

1005-5304

2005

12

6

20-21

10.3969/j.issn.1005-5304.2005.06.009

湖南省教育厅重点资助项目（02A030）；

本校为第一机构

目的研究隔药饼灸对高脂血症兔血浆内皮素(ET)和一氧化氮(NO)含量的影响,阐明隔药饼灸对高脂血症兔ET、NO的调节作用.方法用胆固醇高脂饮食喂养法建立兔高脂血症模型,运用隔药饼灸进行治疗.采用放射免疫法测定治疗后ET的含量,硝酸还原酶法测定NO的含量.结果隔药灸组血浆ET的含量明显低于模型组(P＜0.05),但隔药灸组与直接灸组ET含量无统计学差异(P＞0.05).4组血浆NO的含量虽然有模型组＜空白组＜隔药饼灸组＜直接灸组的趋势,但4组之间两两比较经统计学处理无显著性差异(P＞0.05).结论隔药饼灸和直接灸组均对高脂血症兔血浆ET具有明显调节作用,且二者作用相近.对NO的调节作用不明显.

Objective Through systemetic observation of moxibustion with medicinal cake to the regulated effect of hyperlipemia of the blood-lipid of rabbit, It expounds acting mechanism of this treatment. Method Using high fat diet of cholesterol the model of hypcrlipemia is established. Moxibustion with medicinal cake is used to treat it. Adopting radio-immunity, cholcsterol of endothelin (ET), the nitricoxide (NO) is determined with the method of nitratereductasc. Results The content of plasma ET of group of moxibustion with medicinal cake is obviously lower than that of group of model group, the diffe...