期刊论文

中文

中国中医药信息杂志

1005-5304

2013

20

1

47-49

10.3969/j.issn.1005-5304.2013.01.018

湖南省科技计划项目（2009JT3040）；

本校为第一机构

目的 观察益心泰对心肌梗死后大鼠左室重构的影响.方法 制备心肌梗死大鼠模型.随机分为模型组、益心泰组、开博通组、复方丹参滴丸组和假手术组.模型组和假手术组以蒸馏水等量灌胃,其余各组分别给予相应药物灌胃.用药8周后分别检测左、右心室质量指数及梗死区室壁厚度、室间隔厚度、梗死区面积百分比、心肌纤维直径.结果 与假手术组比较,模型组左、右心室质量指数明显增加(P＜0.01)；与模型组比较,益心泰组、复方丹参滴丸组和开博通组左、右室质量指数均降低(P＜0.01)；而益心泰组、复方丹参滴丸组和开博通组各指标比较差异无统计学意义.与假手术组比较,模型组梗死区室壁厚度、室间隔厚度明显降...

Objective To explore the effect of Yixintai on left ventricular reconstruction of myocardial infarction rats.Methods Myocardial infarction rat model was made.Rats was randomly divided into model group,Yixintai group,Captopril group,compound danshen dripping pills group and sham operation group.The model group and sham operation group were given equivalent distilled water by lavage,the other groups were given corresponding drug.After eight weeks,left and right ventricular weight index,infarction area chamber wall thickness and interventricular s...