期刊论文

Optimization of Extraction Process of Jingfang Children Oral Liquid with Orthogonal Test Based on Information Entropy Theory

中文

中国中医药信息杂志

1005-5304

2018

25

10

91-95

10.3969/j.issn.1005-5304.2018.10.020

本校为第一机构

目的优选荆防小儿口服液的最佳提取工艺。方法以苦杏仁苷转移率、升麻素苷转移率、5-O-甲基维斯阿米醇苷转移率、浸膏得率为评价指标,采用正交试验设计及信息熵理论考察加水量、提取时间对提取工艺的影响。结果荆防小儿口服液的最佳提取工艺条件为:加水量为10倍量,提取时间为1.0 h,回流提取2次。结论本研究优选出的提取工艺简单、稳定,可为荆防小儿口服液的工业化生产提供依据。

Objective To optimize the extraction process of Jingfang Children Oral Liquid. Methods Orthogonal test design and information entropy theory were used to study the influence of water volume and extraction time on extraction process with transferring rates of amygdalin, prim-O-glucosylcimifugin and 5-O-methylvisammioside, and extract yield as evaluation indexes. Results The optimal extraction process conditions were as follows： the ratio of water volume to raw materials weight was 10：1, extraction time was 1.0 h and extracted twice under reflu...