期刊论文

Research Progress of Traditional Chinese Medicine Syndrome Therapy for Psoriasis Based on Metabolomics

中文

中国中医药信息杂志

1005-5304

2020

27

9

136-140

10.3969/j.issn.1005-5304.202001088

国家自然科学基金(81704091) 中国博士后科学基金(2019M653348) 重庆市自然科学基金面上项目(cstc2019jcyj-msxmX0757)。

本校为第一机构

银屑病是临床常见的慢性复发难治性皮肤病之一,中医证候内涵阐释和方药作用机制研究一直是银屑病中医基础研究的热点。代谢组学已广泛运用于中医证候、方药评价、药效基础、中药毒理、针灸效应等多个中医药研究领域。本文综述近年来国内外基于代谢组学技术开展的银屑病中医证治基础研究进展,并就当前银屑病中医证治代谢组学研究中存在问题进行总结和展望,为银屑病中医证候精准诊断、证候演变规律、方药疗效评价及药效物质基础等进一步深入研究提供新思路。

Psoriasis is one of the common chronic relapsing refractory skin diseases in clinic.The interpretation of the connotation of TCM syndromes and the research on the mechanism of prescriptions have always been the focus of basic research on psoriasis.Metabolomics has been widely used in many fields of research in recent years,such as TCM syndromes,formulas evaluation,pharmacodynamic basis,toxicology,acupuncture and moxibustion effect,etc.This article reviewed recent progress in basic research on psoriasis based on metabolomics technology in recent years,summarized and looked forward to the curren...