The theory of disharmony between heart and kidney is an important content of TCM theory, which has positive guiding significance for clinical practice.However, the current understanding and research on this theory is not sufficiently detailed.This article explored and analyzed the theory of disharmony between heart and kidney based on the pathological manifestations and yin-yang, water-fire, ascending and descending, blood and essence, mind, exterior-interior, meridians and collaterals, in order to explore its theoretical connotation, broaden its theoretical...