期刊论文

中文

中国中医药信息杂志

1005-5304

2023

30

07

88-93

10.19879/j.cnki.1005-5304.202206658

82004427:国家自然科学基金 2019M662790:中国博士后科学基金面上项目 2021RC3101:湖湘青年科技创新人才项目 2021ZYX01:湖南中医药大学中医学一流学科开放基金项目

本校为第一机构

目的探讨滋阴明目丸干预视网膜色素变性(RP)模型小鼠的效应及分子机制。方法将12只C57BL/6J小鼠作为正常对照组,48只rd10小鼠随机分为模型组、乐盯组和滋阴明目丸低、高剂量组,分别予相应药物灌胃,连续30 d。H...展开更多 目的探讨滋阴明目丸干预视网膜色素变性(RP)模型小鼠的效应及分子机制。方法将12只C57BL/6J小鼠作为正常对照组,48只rd10小鼠随机分为模型组、乐盯组和滋阴明目丸低、高剂量组,分别予相应药物灌胃,连续30 d。HE染色观察视网膜病理形态,测定外核层厚度和层数;视网膜电图检测视网膜功能,测量A波振幅和B波振幅;光学相干断层扫描检测视网膜全层厚度;数字PCR检测穆勒细胞胶质纤维酸...

Objective To investigate the effect and molecular mechanism of Ziyin Mingmu Pills in mice with retinitis pigmentosa.Methods Totally 12 C57BL/6J mice were set as normal control group,and 48 rd10 mice were randomly divided into model group,Le Ding group,Ziyin Mingmu Pills...MORE Objective To investigate the effect and molecular mechanism of Ziyin Mingmu Pills in mice with retinitis pigmentosa.Methods Totally 12 C57BL/6J mice were set as normal control group,and 48 rd10 mice were randomly divided into model group,Le Ding group,Ziyin Mingmu Pills l...