期刊论文

Peng, QH

英文

Journal of Ethnopharmacology

0378-8741

2024

321

117544

10.1016/j.jep.2023.117544

National Natural Science Foundation of China [81574031]; Hunan Provincial Key Laboratory of Traditional Chinese Medicine Prevention and Treatment of Ophthalmology [2017TP1018]; State Administration of Traditional Chinese Medicine key discipline Construction Project [ZK1801YK015]; Post- graduate Research Innovation in Hunan Province Projects [CX2018B497, CX20200783, CX20210695]; Scientific Research Foundation of Hunan Provincial Education Department [21A0238, 22A0241, 22B0374]; Hunan Provincial Natural Science Foundation [2023JJ40479]

本校为第一且通讯机构

Ethnopharmacological relevance: Modified Danzhi Xiaoyao Powder (MDXP) is a traditional Chinese medicine formula remedy for treating Dry Eye Disease (DED). It showed the function of dispersing stagnated liver Qi for relieving Qi stagnation and clearing heat, which can be effective in treating conditions such as Dry Eye Disease (DED) and irregular menstruation due to liver depression and fire transformation. Aim of the study: This study investigated the mechanism of the effect of MDXP in mice with DED. Materials and methods: A DED model was induced in mice using chronic painful stimulation (tail...