期刊论文、会议论文

中文

中华中医药杂志

1673-1727

2007

22

7

481-483

2009-05-01

10.3969/j.issn.1673-1727.2007.07.018

湖南省社会发展基金资助课题（No.04SK3056）；

本校为第一机构

目的:观察咳喘宁对病毒诱发哮喘患儿T h亚群细胞因子表达的影响。方法:120例病毒诱发哮喘患儿随机分为咳喘宁治疗组60例和西药对照组60例,分别采用咳喘宁、利巴韦林治疗,观察两组患儿治疗后血清中IL-12、IL-4的含量变化。结果:咳喘宁能显著提高患儿血中IL-12,降低IL-4,其作用明显优于对照组。结论:咳喘宁治疗病毒诱发小儿哮喘的机制可能与提高患儿IL-12水平、降低IL4水平有关。

Objective： To observe the effect of Kechuanning on Th cytokine expression in pediatric virus-induced asthma. Methods： 120 cases of pediatric virus - induced asthma were randomly divided into Kechuanning group （treatment group, n = 60, treated with Kechuanning） and Western medicine group （control group, n = 60, treated with virazole）. The change of Thl cytokine IL-12 and Th2 cytokine IL-4 in blood serum were detected and analyzed. Results： Kechuanning could increase IL-12 but decrease IL-4 level in the patient＇s blood, therefore regulate...