期刊论文

中文

中华中医药杂志

1673-1727

2016

31

4

1226-1230

国家自然科学基金项目（No.81073142,No.81270055,No.81173558）~~；

本校为第一机构

目的:探讨用反相气相色谱法(IGC)测定补阳还五汤中阿魏酸的溶度参数的方法评价。方法:将样品均匀地涂布在惰性担体表面上,以N_2气体作为载气,以不同极性的溶剂异丙醇、甲苯、苯、丙酮、氯仿作为探针,热传导检测器检测器温度150℃,气化室温度120℃,采用类似顶空进样方式,取其上空气体1μL进GC测量,测试空气和探针分子在色谱柱内的保留时间t_0、t_R,气体流量F和气相的压力差P_i-P_0等参数结果。结果:根据IGC方法所测到不同探针分子的t_0、t_R、F、P_i-P_0等参数,得出阿魏酸的溶度参数为(24.17±1.30)(J/cm~3)~(1/2),文献值为23.53(J/cm~3)~(1/2),相关系数0.9902。结论:IGC法地测定阿魏酸的溶度参数...

Objective: To investigate the solubility parameter determination of ferulic acid from Buyang Huanwu Decoction with inverse gas chromatography (IGC) method. Methods: The sample was uniformly coated on the surface of an inert carrier and N_2 gas was carrier gas, a variety of polar solvents such as isopropanol, toluene, benzene, acetone and chloroform as probes. TCD detector temperature was 150℃, gas room temperature was 120℃, using similar headspace method that whichever over 1μL gas into the GC measurement, the retention time of air and probe...