期刊论文

中文

中华中医药杂志

1673-1727

2017

32

9

4317-4320

湖南中医药大学感染性疾病中医药防治研究团队基金计划项目(No.Crxjb-12) 湖南省教育厅中医外科学重点学科专项基金资助 湖南省科技厅课题(No.2013SK3097)~~

本校为第一机构

目的:观察湘A1号颗粒治疗艾滋病的临床疗效及安全性,探讨湘A1号颗粒治疗艾滋病的相关机制。方法:采用双盲双模拟设计,将60例艾滋病脾虚湿盛型患者随机分为3组,每组20例。湘A1号组予湘A1号颗粒加抗病毒药物安慰剂;抗病毒组予抗病毒药物加湘A1号颗粒安慰剂;联合组予湘A1号颗粒加抗病毒药物;连续治疗6个月。治疗结束后通过症状体征积分、病毒载量、T细胞亚群进行疗效分析。结果:3组均能有效改善症状体征、提高生活质量(P﹤0.05),湘A1号组与抗病毒组无显著差异,联合组优于湘A1号组和抗病毒组(P﹤0.05);联合组与抗病毒组治疗前后病毒载量计数下降明显(P﹤0.01),且抗病毒作用优于湘A1号组(P﹤0.01);湘...

Objective: To observe the clinical effects and security of Xiang A1 Granules in the treatment of HIV/AIDS, and explore its mechanism. Methods: According to the double-blind, double simulation-trial design, 60 cases of AIDS patients with syndrome of excessive dampness due to spleen deficiency were randomly divided into 3 groups: Xiang A1 group, HAART group and Combination group, 20 cases per group. The Xiang A1 group was administrated with Xiang A1 Granules plus the placebo of HAART; The HAART group was administrated with HAART plus the placebo of Xiang A1 Granules; The Combination group was ad...