期刊论文

Effects of Yougui Pills and its disassembled formula on testis of kidney yang deficiency rats based on ‘reinforcing yang from yin' theory

中文

中华中医药杂志

1673-1727

2018

33

10

4357-4360

国家自然科学基金项目(No.81673984)； 湖南省教育厅优秀青年项目(No.16B200)； 湖南中医药大学“一方研究生科研创新项目”(No.YF201701)； 2017年湖南中医药大学研究生创新课题(No.2017CX32)~~；

本校为第一机构

目的：探讨右归丸及其拆方对肾阳虚雄鼠睾丸组织病理变化的影响。方法：取雄性SD大鼠50只，随机分成正常对照组、模型对照组、补阴药组、补阳药组、全方组，除正常对照组外，其他组建立。肾阳虚动物模型。造模成功后，补阴药组、补阳药组、全方组分别给予相应药物连续灌胃，正常对照组与模型对照组给予等量的0．9％氯化钠溶液灌胃，达疗程后，测定大鼠体质量、睾丸重量、血清中睾酮（T）含量并在光镜下观察睾丸微细结构。结果：与模型对照组比较，右归丸及其拆方均能改善大鼠体质量、睾丸指数、血清T含量（P〈0．05）及大鼠睾丸组织结构，其中全方组的作用最强，而补阴药组提升大鼠体质量作用优...

Objective: To explore the effects of Yougui Pills and its disassembled formula on the pathological changes of kidney yangdeficiency male rats. Methods: Fifty male SD rats were selected and randomly divided into the normal control group, the model group, the nourishing yin group, the tonifying yang group and the whole formula group. Except for the normal control group, the model of kidney yang deficiency was established in other groups. After successful modeling, the nourishing yin group, the tonifying yang group and the whole formula group were given the corresponding medicine for intragastric...