The thought of 'prevention before disease onset' in Huangdi Neijing is rich in connotation, which has important guiding significance for maintaining the health of the body, achieving the ideal state of 'inseparability of the body and spirit' and 'avoid disease'. It is an important part of the thought of preventing disease. With the increasing incidence of male infertility, patients' physical and mental health, family happiness index and human reproduction ability are affected. Based on the thought of 'prevention before disease onset' in Huangdi Neijing, this article analyzes the four preventio...