期刊论文

Effects of dialogue between intestinal microecology and DNA methylation on coronary heart disease with blood stasis syndrome and study of intervention by Chinese herbs

中文

中华中医药杂志

1673-1727

2023

38

2

722-726

No.81874375:国家自然科学基金 No.2022JJ30430:湖南省自然科学基金项目 No.21A0231:湖南省教育厅科学研究重点项目

本校为第一机构

冠心病是一种严重威胁人类健康且发病率较高的疾病,血瘀证是其最主要证型,研究发现肠道微生态和DNA甲基化均与冠心病血瘀证发生有关,且肠道微生态和表观遗传修饰相互影响,肠道微生态失调可能调控宿主表观遗传修饰导致疾病的发生;反...展开更多 冠心病是一种严重威胁人类健康且发病率较高的疾病,血瘀证是其最主要证型,研究发现肠道微生态和DNA甲基化均与冠心病血瘀证发生有关,且肠道微生态和表观遗传修饰相互影响,肠道微生态失调可能调控宿主表观遗传修饰导致疾病的发生;反之表观遗传层面的变化也影响到肠道微生物稳态。中医“心与小肠相表里”理论与现代“肠道菌群失衡可能促发冠心病”相似,且中...

Coronary heart disease(CHD) is a serious threat to human health and has a high morbidity,and blood stasis syndrome is the most important syndrome type. Studies have found that both intestinal microecology and DNA methylation are related to the occurrence of CHD with blo...MORE Coronary heart disease(CHD) is a serious threat to human health and has a high morbidity,and blood stasis syndrome is the most important syndrome type. Studies have found that both intestinal microecology and DNA methylation are related to the occurrence of CHD with blood...