NMR-based metabolomics Reveals Alterations of Electro-acupuncture Stimulations on Chronic Atrophic Gastritis Rats

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成果类型：

期刊论文

作者：

Xu, Jingjing;Zheng, Xujuan;Cheng, Kian-Kai;Chang, Xiaorong;Shen, Guiping;...

通讯作者：

Dong, Jiyang;Yang, Zongbao

作者机构：

[Dong, Jiyang; Zheng, Xujuan; Shen, Guiping; He, Qida; Dong, JY; Yang, Zongbao; Shen, Jiacheng; Xu, Jingjing; Wang, Yadong] Xiamen Univ, Dept Elect Sci, Xiamen 361005, Peoples R China.

[Dong, Jiyang; Zheng, Xujuan; Shen, Guiping; He, Qida; Dong, JY; Yang, Zongbao; Shen, Jiacheng; Xu, Jingjing; Wang, Yadong] Xiamen Univ, Dept Tradit Chinese Med, Xiamen 361005, Peoples R China.

[Cheng, Kian-Kai] Univ Teknol Malaysia, Innovat Ctr Agritechnol, Dept Bioproc & Polymer Engn, Skudai 81310, Johor, Malaysia.

[Chang, Xiaorong; Liu, Mi; Zhang, Yuan] Hunan Univ Chinese Med, Coll Acupuncture & Moxibust, Changsha 410007, Hunan, Peoples R China.

通讯机构：

[Dong, JY; Yang, ZB] X

Xiamen Univ, Dept Elect Sci, Xiamen 361005, Peoples R China.

Xiamen Univ, Dept Tradit Chinese Med, Xiamen 361005, Peoples R China.

语种：

英文

期刊：

Scientific Reports

ISSN：

2045-2322

年：

2017

卷：

期：

页码：

45580

DOI：

10.1038/srep45580

基金类别：

National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81473751, 81371639]; National Key Basic Research Development Program of ChinaNational Basic Research Program of China [2015CB554502]; Natural Science Foundation of Fujian Province of ChinaNatural Science Foundation of Fujian Province [2015Y0032, 2015J05168]; Natural Science Foundation of Guangdong Province of ChinaNational Natural Science Foundation of Guangdong Province [2014A030313005]

机构署名：

本校为其他机构

院系归属：

针灸推拿与康复学院

摘要：

Chronic atrophic gastritis (CAG) is a common gastrointestinal disease which has been considered as precancerous lesions of gastric carcinoma. Previously, electro-acupuncture stimulation has been shown to be effective in ameliorating symptoms of CAG. However the underlying mechanism of this beneficial treatment is yet to be established. In the present study, an integrated histopathological examination along with molecular biological assay, as well as 1H NMR analysis of multiple biological samples (urine, serum, stomach, cortex and medulla) were employed to systematically assess the pathology of...

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NMR-based metabolomics Reveals Alterations of Electro-acupuncture Stimulations on Chronic Atrophic Gastritis Rats

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