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Identification of xanthones from Swertia punicea using high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry

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成果类型:
期刊论文
作者:
Du, Xin-Gang;Wang, Wei;Zhang, Qing-Ying;Cheng, Jun;Avula, Bharathi;...
通讯作者:
Guo, De-An
作者机构:
[Du, Xin-Gang; Guo, De-An] Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai Res Ctr Modernizat Tradit Chinese Med, Shanghai 201203, Peoples R China.
[Du, Xin-Gang; Zhang, Qing-Ying] Peking Univ, Hlth Sci Ctr, Sch Pharmaceut Sci, Beijing 100191, Peoples R China.
[Wang, Wei] Hunan Univ Chinese Med, Sch Pharm, TCM, Changsha 410208, Hunan, Peoples R China.
[Wang, Wei] Hunan Univ Chinese Med, Sch Pharm, Ethnomed Innovat & Dev Lab, Changsha 410208, Hunan, Peoples R China.
[Cheng, Jun] China Agr Univ, Key Lab Urban Agr N, Minist Agr, Beijing 102206, Peoples R China.
通讯机构:
[Guo, De-An] C
Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai Res Ctr Modernizat Tradit Chinese Med, Haike Rd 501, Shanghai 201203, Peoples R China.
语种:
英文
期刊:
Rapid Communications in Mass Spectrometry
ISSN:
0951-4198
年:
2012
卷:
26
期:
24
页码:
2913-2923
基金类别:
Program for Changjiang Scholar and Innovative Team in UniversityProgram for Changjiang Scholars & Innovative Research Team in University (PCSIRT) [985-2-063-112]; Cultivation Fund of the Key Scientific and Technical Innovation Project, Ministry of Education of ChinaMinistry of Education, China [104218]
机构署名:
本校为其他机构
院系归属:
药学院
摘要:
RATIONALE Swertia punicea Hemsl. (Gentianaceae) are used mainly for the treatment of acute bilious hepatitis, cholecystitis, fever, intoxification and jaundice in China, as a traditional Chinese folk medicine. Xanthones as the main chemical components of Swertia punicea have many possible pharmacological properties, such as hepatoprotective and anti-HIV. In order to obtain an overall picture of the xanthones of Swertia punicea, high-performance liquid chromatography diode-array detection/tandem mass spectrometry (HPLC/DAD-ESI-MS n ) was applied...

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