期刊论文

中文

数字中医药(英文)

2096-479X

2023

6

02

210-220

10.1016/j.dcmed.2023.07.010

Hunan Natural Science Foundation Project(2021JJ40551) Scientific Research Project of Hunan Administration of Traditional Chinese Medicine(D2022053) Scientific Research Project of Hunan Provincial Health Commission(B202313057639).

本校为第一机构

目的基于网络药理学预测乌药治疗慢性盆腔炎(CPID)的活性成分和作用靶点,通过动物实验验证并探讨其可能的作用机制,为乌药的临床应用提供科学依据。方法运用网络药理学和分子对接技术筛选乌药治疗CPID的可能有效成分及其作用靶...展开更多 目的基于网络药理学预测乌药治疗慢性盆腔炎(CPID)的活性成分和作用靶点,通过动物实验验证并探讨其可能的作用机制,为乌药的临床应用提供科学依据。方法运用网络药理学和分子对接技术筛选乌药治疗CPID的可能有效成分及其作用靶点;采用大肠杆菌,金黄色葡萄球菌和解脲脲原体的混合菌加机械损伤法建立慢性盆腔炎模型大鼠;采用HE染色观察子宫、输卵管及脾脏的病理...

Objective To predict the active components and action targets of Wuyao(Linderae Radix)in the treatment of chronic pelvic inflammatory disease(CPID)based on network pharmacology,explore possible mechanisms of the treatment through animal experiments,and provide a scienti...MORE Objective To predict the active components and action targets of Wuyao(Linderae Radix)in the treatment of chronic pelvic inflammatory disease(CPID)based on network pharmacology,explore possible mechanisms of the treatment through animal experiments,and provide a scientific basis for clinical applications of Wuyao(Lindera...