A network pharmacological-based study of the mechanism of Liuwei Dihuang pill in the treatment of chronic kidney disease

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作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Xie, Xi;Lou, Hongjun;Shi, Ye;Gan, Guang;Deng, Hanqing;...

通讯作者：

Gao, X

作者机构：

[Ma, Xinwei; Meng, Mingfang; Xie, Xi] Heilongjiang Univ Tradit Chinese Med, Clin Med Coll 1, Harbin, Peoples R China.

[Gao, X; Lou, Hongjun; Gao, Xi] Heilongjiang Univ Tradit Chinese Med, Affiliated Hosp 1, Harbin 150040, Heilongjiang, Peoples R China.

[Shi, Ye; Gan, Guang] Hunan Univ Tradit Chinese Med, Coll Integrated Chinese & Western Med, Changsha, Peoples R China.

[Deng, Hanqing] Hunan Univ Tradit Chinese Med, Clin Med Coll 1, Changsha, Peoples R China.

通讯机构：

[Gao, X ] H

Heilongjiang Univ Tradit Chinese Med, Affiliated Hosp 1, Harbin 150040, Heilongjiang, Peoples R China.

语种：

英文

关键词：

chronic kidney disease;Liuwei Dihuanng pill;mechanism of action;molecular docking;network pharmacology

期刊：

MEDICINE

ISSN：

0025-7974

年：

2023

卷：

102

期：

页码：

e33727

DOI：

10.1097/MD.0000000000033727

基金类别：

Natural Science Foundation of Heilongjiang Province [LH2021H092]

机构署名：

本校为其他机构

院系归属：

中西医结合学院

摘要：

BACKGROUND: Chronic kidney disease (CKD) is a progressive disease that poses a huge economic burden to society. Liuwei Dihuanng pill is an effective treatment for chronic kidney disease, but its treatment mechanism is unclear. The rapid development of network pharmacology has provided new strategies for studying Chinese medicine. METHOD: The traditional Chinese medicine systems pharmacology database and analysis platform was used to obtain the bioactive components and targets of Liuwei Dihuanng pill. The sources for the CKD-related targets were then obtained from the Genecards, OMIM, TTD, and ...

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A network pharmacological-based study of the mechanism of Liuwei Dihuang pill in the treatment of chronic kidney disease

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