This work was supported by the Science Foundation of Hunan Health Commission (No. B202309017571).
机构署名:
本校为第一机构
院系归属:
临床医学院
摘要:
OBJECTIVES: This study seeks to determine if patients with high-grade glioma (HGG) demonstrate glymphatic system (GS) impairments using Diffusion Tensor Imaging Along Perivascular Spaces (DTI-ALPS). Additionally, it aims to examine the factors affecting GS performance and their implications for HGG prognosis. METHODS: The study enrolled fifty HGG patients alongside fifty age- and sex-matched healthy individuals. Each participant underwent diffusion tensor imaging with a Philips 3.0T MRI scanner to assess and compute the ALPS index within periva...