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Analysis of the glymphatic system function in high-grade glioma patients using diffusion tensor imaging along perivascular spaces

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成果类型:
期刊论文
作者:
Tian, Bin;Jiang, Xili;Luo, Xin;Zhang, Wei
通讯作者:
Zhang, W
作者机构:
[Luo, Xin; Tian, Bin] Hunan Univ Chinese Med, Peoples Hosp Hunan Prov 2, Brain Hosp Hunan Prov, Sch Clin Med,Dept Radiol, Changsha 410021, Peoples R China.
[Jiang, Xili; Zhang, Wei] Brain Hosp Hunan Prov, Peoples Hosp Hunan Prov 2, Dept Radiol, Changsha 410021, Peoples R China.
通讯机构:
[Zhang, W ] B
Brain Hosp Hunan Prov, Peoples Hosp Hunan Prov 2, Dept Radiol, Changsha 410021, Peoples R China.
语种:
英文
关键词:
Glymphatic system;MRI;High-grade glioma;DTI-ALPS;Perivascular spaces;Central nervous system
期刊:
BMC Neurology
ISSN:
1471-2377
年:
2025
卷:
25
期:
1
页码:
1-10
基金类别:
This work was supported by the Science Foundation of Hunan Health Commission (No. B202309017571).
机构署名:
本校为第一机构
院系归属:
临床医学院
摘要:
OBJECTIVES: This study seeks to determine if patients with high-grade glioma (HGG) demonstrate glymphatic system (GS) impairments using Diffusion Tensor Imaging Along Perivascular Spaces (DTI-ALPS). Additionally, it aims to examine the factors affecting GS performance and their implications for HGG prognosis. METHODS: The study enrolled fifty HGG patients alongside fifty age- and sex-matched healthy individuals. Each participant underwent diffusion tensor imaging with a Philips 3.0T MRI scanner to assess and compute the ALPS index within periva...

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