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Association between idiopathic pulmonary fibrosis and risk of different pathological types of lung cancer: a Mendelian randomization study

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成果类型:
期刊论文
作者:
Zheng, Hao;Nie, Duorui;Huang, Xuewu
通讯作者:
Xuewu Huang
作者机构:
[Zheng, Hao] Guangzhou Univ Chinese Med, Clin Med Coll 1, Guangzhou, Peoples R China.
[Nie, Duorui] Hunan Univ Chinese Med, Grad Sch, Changsha, Peoples R China.
[Nie, Duorui] Hunan Univ Chinese Med, Coll Pharm, Changsha, Peoples R China.
[Huang, Xuewu] Guangzhou Univ Chinese Med, Canc Ctr, Affiliated Hosp 1, Guangzhou, Peoples R China.
通讯机构:
[Xuewu Huang] C
Cancer Center, First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China
语种:
英文
关键词:
Cancer;Idiopathic pulmonary fibrosis;Lung cancer;European;Mendelian randomization
期刊:
Journal of Cancer Research and Clinical Oncology
ISSN:
0171-5216
年:
2023
卷:
149
期:
10
页码:
7751-7757
基金类别:
This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.
机构署名:
本校为其他机构
院系归属:
药学院
研究生院
摘要:
BACKGROUND: Many epidemiological studies have shown that idiopathic pulmonary fibrosis (IPF) is a risk factor for lung cancer (LC), but these studies do not provide direct evidence of a causal association between the two diseases. We investigated the causal association between IPF and different pathological types of LC based on the Mendelian randomization (MR) study. METHODS: The genome-wide association study (GWAS) data of IPF and LC were obtained from the latest published articles, and instrumental variables (IVs) for analysis were obtained a...

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