Determination of phenolic acids in Prunella vulgaris L.: a safe and green extraction method using alcohol-based deep eutectic solvents

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成果类型：

期刊论文

作者：

Xia, Bohou;Yan, Dong;Bai, Yubing;Xie, Jiachi;Cao, Yi;...

通讯作者：

Liao, Duanfang

作者机构：

[Lin, Limei; Xia, Bohou; Liao, Duanfang; Xie, Jiachi; Yan, Dong; Cao, Yi; Bai, Yubing] Hunan Univ Chinese Med, Coll Pharm, Changsha 410208, Hunan, Peoples R China.

[Lin, Limei; Xia, Bohou; Liao, Duanfang; Xie, Jiachi; Yan, Dong; Cao, Yi; Bai, Yubing] Hunan Univ Chinese Med, Hunan Res Ctr Engn Technol Rapid Test & Removal T, Changsha 410208, Hunan, Peoples R China.

[Lin, Limei; Xia, Bohou; Liao, Duanfang; Xie, Jiachi; Yan, Dong; Cao, Yi; Bai, Yubing] Hunan Univ Chinese Med, Hunan Engn Lab Tox Subst Control & Prevent Techno, Changsha 410208, Hunan, Peoples R China.

通讯机构：

[Liao, Duanfang] H

Hunan Univ Chinese Med, Coll Pharm, Changsha 410208, Hunan, Peoples R China.

语种：

英文

期刊：

Analytical Methods

ISSN：

1759-9660

年：

2015

卷：

期：

页码：

9354-9364

DOI：

10.1039/c5ay02035b

基金类别：

Specialized Research Fund for the Doctoral Program of Higher EducationSpecialized Research Fund for the Doctoral Program of Higher Education (SRFDP) [20124323120004]; Hunan Natural Science FoundationNatural Science Foundation of Hunan Province [13JJ4089]; Postdoctoral Sustentation Fund of Hunan Province [2014RS4009]; [2013ZX09201019]

机构署名：

本校为第一且通讯机构

院系归属：

药学院

摘要：

The extraction of natural products with available green and safe solvents is rather limited. Recently, deep eutectic solvents (DESs) have attracted growing interest as sustainable and safe solvents. However, few studies have applied DESs in the extraction and determination of phenolic acids. Therefore, in the present study, DESs (alcohol-based) were applied to extract rosmarinic acid and salviaflaside, which were the predominant phenolic acids in Prunella vulgaris. The extraction yield acted as the comprehensive evaluation index, and a central composite design (CCD) of the response surface liq...

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Determination of phenolic acids in Prunella vulgaris L.: a safe and green extraction method using alcohol-based deep eutectic solvents

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