期刊论文

Xiang, R.

英文

Colloids and Surfaces B: Biointerfaces

0927-7765

2022

217

112667

10.1016/j.colsurfb.2022.112667

Nation Natural Science Foundation of China [81904060]; Startup Fund of Fujian Medical University [2018QH1004]; Excellent Youth Project of Ed- ucation Department of Hunan Province [21B0367]; Foundation of Hunan University of Chinese Medicine [2020XJJJ013]

本校为第一机构

In recent years, manganese dioxide (MnO2) nanoparticles with unique physicochemical properties have been widely used in many biomedical fields, such as biosensors, contrast agents, tumor therapy, and drug delivery. From these applications, MnO2 nanoparticles have great clinical translation potential. However, by contrast, the in vitro and in vivo biosafety of MnO2 nanoparticles have been deeply and thoroughly clarified for the clinical translation, which hinders their clinical applications. In this work, we deeply investigated the blood safety of MnO2 nanoparticles by conducting a series of in...