期刊论文

中文

中国实验方剂学杂志

1005-9903

2010

16

9

25-28

10.3969/j.issn.1005-9903.2010.09.009

本校为第一机构

目的:探索颈瘤康贴膏剂的最佳成型工艺,以论证该制剂工艺的可行性及合理性.方法:以赋形性、黏附性、柔软性、膜残留性、涂展性、均匀性、皮肤跟随性为评价指标,采用单因素及正交设计试验法,对实验结果作等级一致性检验,选择最优成型工艺参数.结果:制剂配方中以浸膏与辅料按1∶2比例混匀,辅料各成分配比为聚乙烯醇∶海藻酸钠∶甘油∶CMC-Na 0.5∶2∶1∶0.8为宜,成型工艺条件以超声法排气,50℃常压加热干燥2.5 h,含水达30%,炼合最佳.结论:颈瘤康贴膏剂成型工艺合理、可行,适用于工业化生产.

Objective：The goal exploring optimal molding technology for Jingliukang cataplasmata,for demonstrated the feasibility and the Rationality of preparation technology.Method：Using the Tax shape sex,Sticky attach to nature,Softness,Residues of membrane,Extension,Uniformity,skin follow as the targets,Used single factor and Orthogonal design test method,the experimental results has been tested of grading consistency,choose the best molding Technology parameters.Result： In preparation formula mix the extract with the accessories by 1∶ 2 ratio,the ...