期刊论文

中文

中国实验方剂学杂志

1005-9903

2012

18

14

32-35

10.3969/j.issn.1005-9903.2012.14.008

国家自然科学基金项目（30973955）；

本校为第一机构

目的:探讨乙肝宁中糖类成分的吸湿性.方法:以乙肝宁为模型药物,采用不同分离纯化方法得到总多糖、总单糖、总低聚糖成分,干燥,粉碎,测定吸湿百分率及临界相对湿度.运用HPLC-ELSD测定糖类组成.结果:乙肝宁浸膏临界相对湿度为67.3％,总多糖、总单糖、总低聚糖的临界相对湿度分别为78.4％,62.2％,68.3％.总单糖中主要含果糖,低聚糖中小分子糖主要为果糖,葡萄糖,蔗糖.结论:糖类是乙肝宁吸湿性增大的因素之一,其中果糖吸湿性最大.

Objective：To investigate hygroscopicity of carbohydrate composition in Yiganning aqueous extract.Method：With Yiganning grain as a model drug,total polysaccharides,total monosaccharides and total oligosaccharides were obtained by different separation and purifycation method,and then drying,crushing,hygroscopic percentage and critical relative humidity（CRH） were determined.HPLC-ELSD was used to detect carbohydrate composition by gradient elution method.Result：CRH of Yiganning extract was 67.3%,CRH of total polysaccharide,total monosaccharide...