期刊论文

Effects of Huoxue Cuyu Capsule on Rats with Acute Blood Stasis

中文

中国实验方剂学杂志

1005-9903

2013

19

4

270-273

10.13422/j.cnki.syfjx.2013.04.084

本校为第一机构

目的:探讨活血促愈胶囊对急性软组织损伤引起的外伤血瘀证大鼠模型的影响。方法:用自由落体组织损伤法建立外伤血瘀证大鼠模型,造模后,将动物随机分为模型对照组、三七伤药胶囊对照组、活血促愈胶囊低、中、高剂量组（2.75,8.25,16.50 g.kg-1）,每组动物10只,每天测小腿周长及损伤部位的机械刺激痛阈值;各治疗组分别ig相应的药物,共5 d。然后肉眼观察局部组织损伤程度,进行病理组织学检查,并观察活血促愈胶囊对血液流变学的影响,另设正常对照组。结果:活血促愈胶囊能明显抑制外伤血瘀大鼠受伤部位的软組织肿胀（P

Objective： To study the effects of Huoxue Cuyu capsule on acute soft tissue injury in rats with acute blood stasis. Method： The rat model with acute blood stasis was estalished by freely falling mass damsges models. After modeling, rats were at random divided into model control group, Sanqi capsule control groups, low dose group, middle dose groups and high dose group （2.75, 8.25, 16.50 g kg-1） of Huoxue Cuyu capsule, 10 rats each group, calf circumference and the threshold value of mechanical stimulus in injuries was tested every day. Rats...