期刊论文

Liu, HR

英文

Journal of Applied Polymer Science

0021-8995

2020

137

7

48378-

10.1002/app.48378

The authors sincerely appreciate the supports of the National Key Research and Development Program of China (grant no. 2018YFC1105800), Natural Science Foundation of Hunan Province (grant no. 2016JJ2023), the Program for New Century Excellent Talents in University (grant no. NCET‐12‐0170), and the Innovation Base of Hunan Province for Postgraduates (2014–2017). The authors sincerely appreciate the supports of the National Key Research and Development Program of China (grant no. 2018YFC1105800), Natural Science Foundation of Hunan Province (grant no. 2016JJ2023), the Program for New Century Excellent Talents in University (grant no. NCET-12-0170), and the Innovation Base of Hunan Province for Postgraduates (2014?2017).

本校为其他机构

Inflammatory environment in the end-stage osteoarthritis (OA) cartilage defects greatly limits the effectiveness of engineered cartilage. It is critical that developing scaffolds intend to be applied in cartilage tissue engineering (CTE) under this pathological condition. In this study, poly(3-hydroxybutyric acid-co-3-hydroxyvaleric acid) (PHBV) fibrous scaffolds modified by ginsenoside Rg1 could be able to alleviate the dedifferentiation of articular chondrocytes caused by interleukin-1 beta (IL-1 beta), a key inflammatory factor in the pathogenesis of OA. Followed by 5-day incubation with cu...