The expression of MMP19 and its clinical significance in glioma

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成果类型：

期刊论文

作者：

Luo, Qisheng;Luo, Hongcheng;Chen, Xiaoping;Yan, Peng;Fu, Huangde;...

通讯作者：

Tang, QL

作者机构：

[Tang, Qianli; Luo, Qisheng] Hunan Univ Chinese Med, Coll Integrated Chinese & Western Med, Changsha 410208, Hunan, Peoples R China.

[Yan, Peng; Zheng, Chuanhua; Lan Chuanliu; Huang, Huadong; Li, Chuanyu; Huang, Haineng; Luo, Qisheng; Qin, Chengjian; Fu, Huangde] Youjiang Med Univ Nationalities, Dept Neurosurg, Baise, Guangxi, Peoples R China.

[Luo, Hongcheng] Youjiang Med Univ Nationalities, Dept Lab Med, Baise, Guangxi, Peoples R China.

[Tang, Qianli] Youjiang Med Univ Nationalities, Dept Surg, Baise, Guangxi, Peoples R China.

[Chen, Xiaoping] Guangxi Zhuang Autonomous Reg Peoples Hosp, Dept Neurol, Nanning, Guangxi, Peoples R China.

通讯机构：

[Tang, QL ] H

Hunan Univ Chinese Med, Coll Integrated Chinese & Western Med, Changsha 410208, Hunan, Peoples R China.

语种：

英文

关键词：

MMP19;overexpression;glioma;disease progression;outcome

期刊：

International Journal of Clinical and Experimental Pathology

ISSN：

1936-2625

年：

2018

卷：

期：

页码：

5407-5412

基金类别：

National Natural Science Foundation of China [81760450]; Guangxi Natural Science Foundation of China [2017GXNSFAA198322]

机构署名：

本校为其他机构

院系归属：

中西医结合学院

摘要：

Aims: The expression of phosphoglycerate kinase 1 (MMP19) is elevated in some cancers. However, the clinical features and prognostic value of glioma patients with MMP19 expression are unclear. In this study, the expression level of MMP19 and the correlation between the level of MMP19 expression and the clinicopathologic data in glioma patients including survival were examined. Methods and results: Using real-time PCR, the mRNA expression of MMP19 was examined in 61 fresh glioma tissues and 32 brain samples. The result indicated that MMP19 mRNA was obviously elevated in glioma tissues compared ...

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The expression of MMP19 and its clinical significance in glioma

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