Hunan National Science Funds [2017JJ2343]; Hunan Provincial Administration of Traditional Chinese Medicine Research Project Fund [201894]; Hunan Provincial Brain Hospital Key Scientific Research Project [2017A02]; Key R&D Program of Hunan Province [2018SK1030]; Changsha Social Work College National Project Cultivation Project
机构署名：
本校为通讯机构
院系归属：
中医学院
药学院
摘要：
Traumatic brain injury (TBI) is a major source of mortality and long-term disability worldwide. The mechanisms associated with TBI development are poorly understood, and little progress has been made in the treatment of TBI. Tanshinone IIA is an effective agent to treat a variety of disorders; however, the mechanisms of Tanshinone IIA on TBI remain unclear. The aim of the present study was to investigate the therapeutic potential of Tanshinone IIA on TBI and its underlying molecular mechanisms. Changes in microvascular permeability were examined to determine the extent of TBI with Evans blue d...
