The Effect of Hedysarum multijugum Maxim.-Chuanxiong rhizoma Compound on Ischemic Stroke: A Research Based on Network and Experimental Pharmacology

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成果类型：

期刊论文

作者：

Yang, Kailin;Zeng, Liuting*;Ge, Anqi;Shi, Yongmei;Zhu, Xiaofei;...

通讯作者：

Ge, Jinwen;Zeng, Liuting

作者机构：

[Yang, Kailin; Ge, Anqi] Hunan Univ Chinese Med, Affiliated Hosp 1, Changsha, Hunan, Peoples R China.

[Zhu, Xiaofei; Yang, Kailin; Shi, Yongmei; Ge, Jinwen; Liu, Wenlong] Hunan Univ Chinese Med, Changsha, Hunan, Peoples R China.

[Yang, Kailin] Capital Med Univ, Beijing, Peoples R China.

[Zeng, Liuting] Chinese Acad Med Sci & Peking Union Med Coll, Peking Union Med Coll Hosp, Dept Rheumatol & Clin Immunol, Beijing, Peoples R China.

通讯机构：

[Ge, Jinwen] H

[Zeng, Liuting] C

Hunan Univ Chinese Med, Changsha, Hunan, Peoples R China.

Chinese Acad Med Sci & Peking Union Med Coll, Peking Union Med Coll Hosp, Dept Rheumatol & Clin Immunol, Beijing, Peoples R China.

语种：

英文

期刊：

Oxidative Medicine and Cellular Longevity

ISSN：

1942-0900

年：

2020

卷：

2020

DOI：

10.1155/2020/6072380

基金类别：

National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81774074]; National Key Research and Development Project of China [2018YFC1704904]

机构署名：

本校为第一且通讯机构

院系归属：

第一中医临床学院

摘要：

Background.Hedysarum multijugum Maxim.-Chuanxiong rhizomacompound (HCC) is a common herbal formula modified from Buyang Huanwu decoction. Clinical trials have demonstrated its therapeutic potential for ischemic stroke (IS). However, the mechanism of HCC remains unclear.Methods. The HCC's components were collected from the TCMSP database and TCM@Taiwan database. After that, the HCC's compound targets were predicted by PharmMapper. The IS-related genes were obtained from GeneCards, and OMIM and the protein-protein interaction (PPI) data of HCC's targets and IS genes were obtained from the String...

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The Effect of Hedysarum multijugum Maxim.-Chuanxiong rhizoma Compound on Ischemic Stroke: A Research Based on Network and Experimental Pharmacology

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