The objective of the study was to study the protective effect of Silybum marianum extract on hepatic ischemiareperfusion injury. Rats were randomly divided into five groups; namely Silybum marianum extract high-, medium-, and lowdose protection groups, model group and control group. Hepatic ischemia-reperfusion injury model was prepared. Serum or plasma AST, ALT, MDA, TNF-α, IL-1β, IL-6 levels were measured. The results revealed that after liver injury, AST, ALT, MDA, TNF-α, IL-1β, and IL-6 levels significantly increased in succession, show...