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A sensitive electrochemical aptasensor for zearalenone detection based on target-triggered branched hybridization chain reaction and exonuclease I-assisted recycling

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成果类型:
期刊论文
作者:
Liao, Zhibing;Guo, Wentao;Ning, Guiai;Wu, Yaohui;Wang, Yonghong;...
通讯作者:
Wang, YH;Ning, G
作者机构:
[Ning, Guiai; Liao, Zhibing; Wu, Yaohui; Guo, Wentao; Wang, Yonghong] Cent South Univ Forestry & Technol, Hunan Prov Key Lab Forestry Biotechnol & Int Coope, Base Sci & Technol Innovat Forest Resource Biotech, Changsha 410004, Peoples R China.
[Wang, Yonghong] Yuelushan Lab, Changsha 410004, Peoples R China.
[Ning, Ge; Ning, G] Hunan Univ Chinese Med, Int Educ Inst, Changsha 410208, Peoples R China.
通讯机构:
[Wang, YH ] C
[Ning, G ] H
Cent South Univ Forestry & Technol, Hunan Prov Key Lab Forestry Biotechnol & Int Coope, Base Sci & Technol Innovat Forest Resource Biotech, Changsha 410004, Peoples R China.
Yuelushan Lab, Changsha 410004, Peoples R China.
Hunan Univ Chinese Med, Int Educ Inst, Changsha 410208, Peoples R China.
语种:
英文
关键词:
Zearalenone;Exonuclease I;Branched hybridization chain reaction;Electrochemical
期刊:
Analytical and Bioanalytical Chemistry
ISSN:
1618-2642
年:
2023
卷:
415
期:
20
页码:
4911-4921
基金类别:
This work was supported in part by the Hunan Provincial Natural Science Foundation of China (2021JJ31138), the Scientific Research Fund of Hunan Provincial Education Department (20A520), and the Training Program for Excellent Young Innovators of Changsha (kq2106053).
机构署名:
本校为通讯机构
院系归属:
国际教育学院
摘要:
Traditional methods for detecting antibiotic and mycotoxin residues rely on large-scale instruments, which are expensive and require complex sample pretreatment processes and professional operators. Although aptamer-based electrochemical sensors have the advantages of simplicity, speed, low cost, and high sensitivity, most aptamer-based sensors lack a signal amplification strategy due to their direct use of aptamers as probes, resulting in insufficient sensitivity. To solve the sensitivity problem in the electrochemical detection process, a nov...

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