期刊论文

Study on the Clinical Efficacy of Traditional Chinese Medicine in Treating Liver Cancer with Liver Depression and Spleen Deficiency Based on the Theory of Correspondence of Formula and Syndrome

中文

世界科学技术-中医药现代化

1674-3849

2021

23

01

67-74

10.11842/wst.20200515004

国家自然科学基金委员会面上项目（81473617）:活血化瘀中药独立于抗凝作用外的抗炎-抗肝癌途径分子机制及"扶正"配伍研究,负责人:田雪飞； 湖南中医药大学研究生创新课题（2020CX14）:基于网络药理学预测的AGE-RAGE信号通路研究疏肝健脾消癌方治疗肝癌机制,负责人:张振；

本校为第一机构

目的 基于方证对应理论探讨中医药治疗肝郁脾虚型肝癌临床及用药规律.方法 根据服用中药时间将患者分成中药弱暴露(less-CM)组及中药强暴露(CM)组,评价2组患者生存时间(OS)及无进展生存时间(PFS);利用中医传承辅助平台,对CM组患者处方进行分析.结果 CM组患者在OS及PFS优于Less-CM组(P

Objective To explore the clinical and pharmacological rules of traditional Chinese medicine (TCM) in the treatment of liver cancer with liver depression and spleen deficiency based on the theory of correspondence between formula and syndrome.Methods Patients were divided into Chinese medicine weak exposure (less-CM) group and Chinese medicine strong exposure (CM) group according to the time of taking Chinese medicine,and the survival time(OS) and progression-free survival time (PFS) of patients in the 2 groups were evaluated;the prescriptions of patients in the CM group were analyzed by using ...